Saturday, November 13, 2004

Drinking Sucrose Before Exercise Helpful in McArdle's Disease

"Drinking a sucrose beverage before exercise improves exercise capacity and sense of well being for patients with McArdle's disease, according to the results of a single-blind, randomized trial published in the Dec. 25 issue of the New England Journal of Medicine. The perspective writer agrees that this intervention can be helpful."

Patients With Stable CAD May Not Benefit From Adding an ACE ...

"Patients with stable coronary artery disease (CAD) do not benefit from the addition of an angiotensin-converting enzyme (ACE) inhibitor, particularly trandolapril, according to the results of a randomized study published in the Nov. 11 issue of the New England Journal of Medicine."

Thursday, November 11, 2004

Sports Injuries in Children

Sports Injuries in Children: "In recent years, medical and lay media have publicized the epidemic of obesity in Americans. Further, the last four decades have seen a disturbing increase in sedentary lifestyles in adults. Youth are also more sedentary, largely due to the influence of television watching and hours of indulgence in video games and online chats, activities that neglect cardiovascular fitness and do not exercise major muscle groups."

Wednesday, November 10, 2004

Mutations in Glucocerebosidase Gene Linked to Parkinson's Disease

"Mutations in the glucocerebosidase gene (GBA) appear to increase the risk of idiopathic Parkinson's disease, according to findings of study involving Ashkenazi Jews. Previous reports have shown type 1 Gaucher's disease, which is caused by certain GBA mutations, is associated with parkinsonism. However, the role of GBA mutations in idiopathic Parkinson's disease was unclear."

Antibiotics Do Not Appear to Prevent Recurrent Cardiac Events

"Antibiotics targeting Chlamydia pneumoniae do not reduce cardiac events or mortality in patients with ischemic heart disease, according to a report in the October 25th issue of the Annals of Internal Medicine."

Antibiotics Do Not Appear to Prevent Recurrent Cardiac Events

"Antibiotics targeting Chlamydia pneumoniae do not reduce cardiac events or mortality in patients with ischemic heart disease, according to a report in the October 25th issue of the Annals of Internal Medicine."

High-Dose Atorvastatin Can Slow Progression of Alzheimer's Disease

"Results from a placebo-controlled pilot study of statin therapy for the treatment of mild Alzheimer's disease suggest that 80 mg of atorvastatin daily can stabilize or slow progress of the disease, a finding that the lead investigator characterized as a 'proof of concept.'"

Orlistat Plus Lifestyle Changes Can Reduce the Incidence of Type

"Orlistat combined with lifestyle modifications reduces the incidence of type 2 diabetes, according to the results of a randomized trial published in the January issue of Diabetes Care. A related study in the same issue showed that in type 2 diabetics, use of orlistat results in greater improvement in free fatty acid (FFA) levels and insulin sensitivity (IS) with the same degree of weight loss. On Dec. 15, the U.S. Food and Drug Administration approved orlistat, an intestinal lipase inhibitor, for 12- to 16-year-olds."

DHEA May Reduce Abdominal Fat and Increase Insulin Sensitivity in the...

"Daily replacement therapy with 50 mg of dehydroepiandrosterone (DHEA) significantly decreases visceral and subcutaneous abdominal fat and significantly increases insulin sensitivity in the elderly, according to the results of a six-month, randomized, double-blind, placebo-controlled preliminary trial published in the Nov. 10 issue of JAMA."

Carvedilol Does Not Appear to Worsen Glycemic Control and May Improve...

"Carvedilol does not appear to worsen glycemic control and may improve some components of the metabolic syndrome in patients with diabetes and hypertension, according to the results of a randomized, double-blind, parallel-group trial published in the Nov. 10 issue of JAMA. The findings were also presented Tuesday at the American Heart Association Scientific Sessions in New Orleans"

Patients Who Have Had ORS May Be Revaccinated Safely

"Patients who have had oculorespiratory syndrome (ORS) can be revaccinated safely, according to the results of a randomized trial published in the November issue of the Archives of Internal Medicine."

Amlodipine May Reduce Adverse CV Events in Normotensive...

"Amlodipine reduces adverse cardiovascular (CV) events in patients with coronary artery disease (CAD) and normal blood pressure (BP), according to the results of a randomized trial published in the Nov. 10 issue of JAMA. Intravascular ultrasound (IVUS) in these patients also suggests a slowing of atherosclerotic progression."

Tight BP Control May Reduce Risk of Diabetic Retinopathy

"Tight blood pressure (BP) control can reduce the risk of diabetic retinopathy, according to the results of a randomized controlled trial published in the November issue of the Archives of Ophthalmology."

Atenolol May Not Protect Against Heart Disease

"Atenolol may not protect against heart disease and actually may be harmful, according to the results of an analysis of trials published in the Nov. 6 issue of The Lancet."

Tight BP Control May Reduce Risk of Diabetic Retinopathy

"Tight blood pressure (BP) control can reduce the risk of diabetic retinopathy, according to the results of a randomized controlled trial published in the November issue of the Archives of Ophthalmology."

Dietary Viscous Fiber Reduces Progression of Carotid IMT

"Dietary viscous fiber can reduce progression of carotid intima-media thickness (IMT), according to the results of a prospective trial published in the December issue of the American Journal of Clinical Nutrition. This benefit appears to be partially mediated through an effect on the lipid profile."

Monday, November 08, 2004

Shuttle Walk Test Often as Reliable as Treadmill Testing for...

"The shuttle walk test is as reliable as treadmill testing, evokes less cardiovascular stress, and is preferred by patients for the evaluation of claudication, according to the results of a study published in the November issue of Medicine and Science in Sports & Exercise."

High-Intensity Exercise May Be Helpful in Rheumatoid Arthritis

"High-intensity exercise does not increase joint damage in rheumatoid arthritis (RA) and may even be protective, according to the results of a randomized trial published in the November issue of the Annals of the Rheumatic Diseases."