Orlistat Plus Lifestyle Changes Can Reduce the Incidence of Type

"Orlistat combined with lifestyle modifications reduces the incidence of type 2 diabetes, according to the results of a randomized trial published in the January issue of Diabetes Care. A related study in the same issue showed that in type 2 diabetics, use of orlistat results in greater improvement in free fatty acid (FFA) levels and insulin sensitivity (IS) with the same degree of weight loss. On Dec. 15, the U.S. Food and Drug Administration approved orlistat, an intestinal lipase inhibitor, for 12- to 16-year-olds."