bmj.com Chowdhury et al. 327 (7423): 1059: "Editorial Preventing diabetes in south Asians Too little action and too late The south Asian diaspora in the United Kingdom comprises Indians (predominantly Gujaratis and Punjabis), Sri Lankans, Pakistanis, and Bangladeshis. A dramatic increase in the prevalence of type 2 diabetes in south Asians is observed in many parts of the world including the United Kingdom.1 While marked cultural and social differences arise within this racial group, south Asians have the unenviable distinction of achieving the highest death rates of coronary heart disease in the United Kingdom,2 with Bangladeshis being particularly disadvantaged..."

A must-read for all the aspiring Physicians! - KK

Antimalarial Regimen tolerated well: "Common antimalarial regimens are well tolerated Doxycycline and combined atovaquone and proguanil are the best tolerated of four recommended antimalarial regimens. In a randomised double blind controlled trial Schlagenhauf and colleagues (p 1078) assessed chemoprophylaxis in more than 600 non-immune travellers to sub-Saharan Africa. A high proportion of participants reported adverse events. Skin problems were more common in travellers taking chlorequine and proguanil, and patients taking mefloquine had more neurophysiological adverse events."

DVT within two weeks of flight: "Deep vein thrombosis is most likely within two weeks of long flights An aeroplane passenger has four times the risk of venous thromboembolism, but only in the first two weeks after a long haul flight. Kelman and colleagues (p 1072) linked hospital records for 5408 patients admitted to hospital with venous thromboembolism to arrival data for international flights during 1981-99 in Western Australia. They conclude that for most passengers the risk of venous thromboembolism after a long haul flight is small and that the average risk of death from flight related venous thromboembolism is around 1 per 2 million flights."

Interesting info! - KK

The Journal : Current Issue: "Open access to peer-reviewed research: making it happen Pritpal S Tamber, Fiona Godlee, Peter Newmark Lancet 2003; 362: 1575-77"

Must read for anyone interested in the concept of open access journals! - KK

NEJM -- Effect of CD3{delta} Deficiency on Maturation of {alpha}/{beta} and {gamma}/{delta} T-Cell Lineages in Severe Combined Immunodeficiency: "Effect of CD3 Deficiency on Maturation of /?? and / T-Cell Lineages in Severe Combined Immunodeficiency."

NEJM -- Extraneural Pathologic Prion Protein in Sporadic Creutzfeldt-Jakob Disease: "Extraneural Pathologic Prion Protein in Sporadic Creutzfeldt–Jakob Disease"

NEJM -- A Randomized Trial of Letrozole in Postmenopausal Women after Five Years of Tamoxifen Therapy for Early-Stage Breast Cancer: "A Randomized Trial of Letrozole in Postmenopausal Women after Five Years of Tamoxifen Therapy for Early-Stage Breast Cancer"