Long-Term NSAIDs May Not Be Useful for Osteoarthritis

Nonsteroidal anti-inflammatory drugs (NSAIDs) offer only a small, short-term benefit that may not be clinically significant for people with knee osteoarthritis (OA), according to the results of a meta-analysis published in the Nov. 30 Online First issue of the BMJ. Due to the long-term harm and lack of demonstrated benefit, the investigators recommend against long-term use of NSAIDs for OA."