Adding Thiazolidinedione to Metformin Plus Insulin Improves Glycemic Control

Adding thiazolidinedione to metformin (MET) plus insulin (INS) improved glycemic control and reduced INS dose without increasing weight gain, according to the results of a randomized trial published in the July issue of Diabetes Care. The editorialist suggests that treating to target is all that matters, regardless of what combination of medications is used. Cost and lifestyle should be considered in choosing optimal triple therapy.

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