GlycoMark Assay Reflects Glycemic Control

"The first U.S. trial of the GlycoMark assay, reported in the August issue of Diabetes Care, demonstrated that 1,5-anhydroglucitol (1,5-AG) levels are a good indicator of glycemic control. This assay has Food and Drug Administration (FDA) clearance for intermediate term monitoring. '1,5-Anhydroglucitol (1,5AG) is a major circulating polyol arising primarily from ingestion and excreted competitively with glucose,' write Janet B. McGill, MD, from the Washington University School of Medicine in St. Louis, Missouri, and colleagues. 'Japanese studies have demonstrated reduced concentrations of 1,5AG in serum in hyperglycemic patients in comparison with euglycemic subjects and a gradual normalization of 1,5AG values for patients responding to antihyperglycemic therapies.'"